Tired of guessing which advanced actives are beneficial to your skin? You’ve probably heard about exosome skincare and how it can make your skin look younger, firmer, and more radiant.
Exosomes are nanoscale messengers that cells naturally release to help coordinate renewal and repair.
PTT-6®, a patented combination of stem cell-derived proteins, cytokines, growth factors, and exosomes, is used in CALECIM skin care products to deliver regenerative signals and promote healthy skin behavior.
Contents
What Are Exosomes, and Why Do They Matter in Skin?
Exosomes are nanosized extracellular vesicles (approximately 30-150 nm) secreted by most cells. They transport proteins, lipids, and nucleic acids (RNA and microRNA) that can influence the behavior of other cells.
In vitro and preclinical studies indicate that exosomes can help to modulate inflammation and support extracellular matrix renewal, which are mechanisms involved in photoaging, wound healing, and post-procedure recovery. Clinical dermatology reviews state that the field is promising but still in its early stages.
How CALECIM® utilizes exosome science (PTT-6®)
CALECIM® Professional leverages exosome science through PTT-6®, a proprietary stem-cell-derived complex containing thousands of proteins, growth factors, cytokines, and exosomes. These extracellular vesicle signals function as “youth messages,” encouraging sluggish skin caused by age or procedures to behave more youthfully. They aid in repair coordination by increasing cell turnover, proliferation, and migration, as well as promoting a healthier extracellular matrix. PTT-6® is intended to stimulate collagen, elastin, and hyaluronic acid production, which has been linked to smoother texture, increased elasticity, and improved hydration in dermatology literature.
Calecim reported important in vitro results, including:
- 56% increase in elastin expression
- 83% increase in hyaluronic acid production
- 42% more skin cell growth at 7 days
- Up to 600% improvement in skin density
Who benefits most? Age-specific recommendations
Skin changes are gradual but measurable. Dermal collagen declines with age (approximately 1% per year across adult life), leading to thinning and laxity. Additionally, hyaluronic acid (HA) content and water-binding capacity decrease, affecting plumpness and glow.
20s to early 30s: Prevention and recovery
- What’s happening: Lifestyle and UV light are largely responsible for the noticeable change in collagen production, which starts a long, gradual decline.
- How exosomes skin care can help: The early use of Calecim skincare products can help support renewal signals and maintain a healthy turnover rhythm. It can also be used in conjunction with sunscreen and antioxidants and after stressful events like late nights, travel, and sun exposure.
30s to 40s: Texture, dullness, first laxity
- What’s happening: Subtle laxity, fine lines, uneven tone; HA and collagen pathways are slow; recovery time after procedures may be longer.
- How exosomes skin care can help: Calecim Professional Serum contains the highest concentration of PTT-6®, which can keep skin supple and healthy while targeting fine lines, wrinkles, and hyperpigmentation. Calecim serum is compatible with other active ingredients and in-clinic procedures (such as lasers or microneedling), which have been shown to reduce fine lines and wrinkles, improve skin texture and elasticity, and promote healing.
40s to 50s+: Laxity, dryness, thinning
- What’s happening: More noticeable collagen/elastic fiber changes and water loss; the menopausal transition frequently causes dryness and sensitivity.
- How exosomes skin care can help: Calecim Professional Multi-Action Cream promotes firmness, deep hydration, and luminosity while complementing professional treatments. It stimulates collagen and elastin production to effectively lift and firm the skin, as well as repair and restore it across layers for a healthy, supple, and radiant complexion.
Who benefits most? Skin-type guidance
Sensitive/reactive
Choose fragrance-free, minimalist routines, and patch-test new products before applying them to your face. Unlike other products that can irritate the skin, CALECIM® skincare formulas are gentle on sensitive and post-treatment skin and have no negative side effects. However, patch testing remains the gold standard in dermatology.
Dry/dehydrated
Prioritize routines that promote hyaluronic acid. Age-related HA decline reduces water-binding capacity, which is one of the reasons why skin appears dull. Hydrating creams (such as Restorative Hydration Cream) can be used to revitalize and replenish dry, dull skin, as well as visibly increase suppleness.
Oily/acne-prone
Look for lightweight textures and acne-friendly habits (gentle cleansing and no overscrubbing). Calecim Professional skincare products are suitable for all skin types, including those prone to acne or clogged pores.
Post-procedure (in-clinic care)
Clinics frequently combine exosome skin care with lasers, microneedling, and energy devices to aid in visible recovery and improve cosmetic results.CALECIM® products, such as Professional Serum, can be applied after microneedling and have been shown to promote faster healing and skin regeneration.
FAQ: Quick answers
Will exosomes help sensitive skin?
Yes, gentle formulas such as Calecim are hydrating and barrier-supportive, making them ideal for sensitive skin. However, patch testing is recommended first
At what age should I start?
There’s no “right” age, but starting in your late 20s–30s is reasonable if you’re chasing prevention and enhanced recovery after procedures. Collagen synthesis slows with age, and HA content decreases beginning in early adulthood; earlier support can help maintain skin quality.
Is exosome skincare safe after treatments like lasers or microneedling?
Yes, exosomes can speed up healing, reduce redness, and improve rejuvenation outcomes after treatment.
The bottom line
Exosome skincare aims to provide skin with more precise “repair signals,” allowing it to function more youthfully.
CALECIM® Professional’s PTT-6® is a concentrated, cosmetic-grade blend of stem-cell-derived proteins, growth factors, cytokines, and exosomes that promotes turnover, hydration, and visible firmness in all age groups and skin types, especially when combined with sunscreen and used consistently.
Ready to upgrade your skincare approach? Visit Calecim Professional to learn how exosome-powered precision can rejuvenate your skin’s future today.
