If you are dealing with texture issues, you might already know that atrophic scars require more than just surface-level creams. The solution often lies in a two-step approach: Professional microneedling combined with CALECIM® Professional Serum.
This combination targets the structural deficits of scars, allowing you to maintain those gains with daily regenerative skincare.
Here’s a deep dive into how it works and what the evidence says.
Contents
Get Rid of Old Acne Scars with CALECIM® Professional
The protocol is straightforward but precise. It utilizes clinician-performed microneedling to open precise micro-channels in the skin. From there, the dermis is saturated with CALECIM® Professional Serum (PTT-6®) both during and immediately after the treatment.
This is followed by a short recovery period and daily CALECIM® skincare to consolidate the remodelling. While microneedling improves atrophic scars on its own, adding CALECIM®’s PTT-6® introduces growth-factor and exosome signals. These stimulate the key matrix components required to restore volume and elasticity.
Why this works:
The Mechanism: PTT-6® contains a potent mix of growth factors, cytokines, exosomes, and peptides that signal to your cells. The tiny channels created by microneedling help these messages reach the deeper layers where they are needed most.
The Measured Effects: A study by CellResearchCorp showed impressive stats, including an 83% increase in hyaluronic acid, a 56% rise in elastin, an average 600% improvement in skin thickness, and a 42% growth in skin cells within just 7 days.
Who it’s for: It is designed for patients with atrophic scars (boxcar, rolling, or ice-pick) after active acne has settled. It is generally suitable across many skin tones with appropriate medical oversight.
The Timeline: Typically, this involves multiple sessions spaced several weeks apart, with a continued home regimen to help with visible results.
Comparing Scar Revision Options: CALECIM® PTT-6® vs. Traditional Therapies
Microneedling (collagen induction therapy) is globally recognized as a gold-standard mechanical method for treating atrophic scars. However, aesthetic professionals generally concur that combining microneedling with potent topical growth factors—which actively promote comprehensive dermal remodelling—gives optimal results.
Depending on the severity of the scarring and your desired outcome, here is how the “Regenerative Approach” compares to standard options:
| Therapy | Pros | Cons |
| CALECIM® PTT-6® + Microneedling | Targeted molecular signalling for precision repair. Delivers up to 600% improvement in density and promotes significant HA (83%) and elastin (56%) production. High efficacy for established scarring. | Requires a structured, multi-session clinical protocol. |
| Microneedling (Monotherapy) | Initiates a general wound healing cascade, thereby stimulating some collagen production. It is minimally invasive. | Outcomes may be less predictable and can sometimes yield structurally disorganized scar tissue. Lacks specific molecular instructions for HA or Elastin synthesis. |
| Platelet-Rich Plasma (PRP) + Microneedling | Utilizes the patient’s own growth factors present in their blood. | Requires blood collection and processing. Efficacy can be variable based on the patient’s age and overall health status. |
Step-by-Step How-To
If you are ready to start, here is what the process looks like:
1. Skin Stabilization and Pre-Treatment (2–12 weeks)
First, ensure there is no active acne or infection before needling and always treat inflammation first. According to the JDD, contraindications include active acne, keloid tendency, local infection, and immunosuppression.
Tip: Build tolerance with gentle skincare and avoid irritants a few days before your session as advised by your clinician.
2. Treatment Day: In-clinic Microneedling & PTT-6® Delivery
A licensed clinician will perform microneedling to a controlled depth. They will then apply CALECIM® Professional Serum during and after passes so the signals reach the dermis via fresh micro-channels.
Rationale: Microneedling has RCT-level support for atrophic scars. Adding a signalling complex supplies specific HA/elastin-directed cues.
3. Post-Procedure Recovery (First 24–72 hours)
Continue using the Professional Serum to support comfort and reduce visible downtime. You can resume your usual activities only after re-epithelialization, as advised by your clinician.
Aftercare: Gentle hydration (e.g., Restorative Hydration Cream) and barrier care can be layered as directed.
Safety note: Microneedling is a medical procedure. Always see a board-certified dermatologist or qualified medical professional, especially for darker skin types, a history of PIH, or if you’re on anticoagulants or retinoids. Avoid treatment with active herpes lesions; clinicians may use antiviral prophylaxis when indicated.
FAQs
Is CALECIM® PTT-6® proven to affect the building blocks scars need?
Yes. In lab tests, PTT-6® increased hyaluronic acid by 83% and elastin by 56%, leading to about a 600% improvement in skin thickness and a 42% increase in skin-cell growth after 7 days.
Is it possible to use microneedling without incorporating serums?
Yes, microneedling alone improves atrophic acne scars in all skin types. However, adding regenerative signals, such as CALECIM® serum, is a clinician-friendly way to target HA/elastin specifically and promote recovery.
Is at-home microneedling okay?
As microneedling is a medical procedure with infection and PIH risks, professional care is recommended. If you do use an at-home device, follow strict hygiene and product guidance, and never treat active acne.
Clinical evidence
Does it work in the real world? According to Adrian Baker’s detailed case study, the combination of CALECIM® Professional Serum and microneedling resulted in the near-complete resolution of established acne scarring in an adult patient. This confirms the serum’s functional role in volumetric correction and tissue remodelling.
Where to Buy & How to Start
Ready to address old scars? Because the CALECIM® Professional Serum is a high-concentration formula designed for use during active treatment, it is best experienced in a clinic setting.
- Find a Professional: You can locate a certified partner clinic offering the PTT-6® microneedling protocol via the CALECIM® Clinic Locator.
- Maintenance at Home: To maintain your results between sessions, you can purchase the daily regenerative skincare line (including the Restorative Hydration Cream) directly from the CALECIM® official website or through your aesthetic provider.
Have you tried regenerative skincare for scarring before? Share your experience in the comments below!
